Funding

AusperBio raises $120M Series C to advance hep B oligo therapy through phase 3

August 28, 2026

Biotech

Funding

Key Facts

Signal Type

Funding

Industry

Biotech

Companies

AusperBio Therapeutics, RA Capital Management, GSK, Ionis Pharmaceuticals, Qiming Venture Partners

Date

August 28, 2026

What Happened

AusperBio Therapeutics raised $120 million in Series C funding led by RA Capital Management, with participation from HanKang Capital, Qiming Venture Partners, YuanBio Venture Capital, and CDH Investments. The Bay Area biotech is advancing lead candidate AHB-137, an unconjugated antisense oligonucleotide (ASO) for chronic hepatitis B, into Phase 3 testing in China. The round follows a $37M Series A in 2024 and a three-part $186M Series B across 2024-25.

Who Is Affected

This funding impacts clinical research organizations, lab informatics vendors, and specialty supply chain partners targeting biotech scale-ups. AusperBio is preparing to scale clinical operations, manufacturing, and data infrastructure for Phase 3 and potential commercialization. Competitors like GSK's bepirovirsen (licensed from Ionis) are also advancing in the oligonucleotide space.

Market Impact

  • Clinical Trial Demand: Phase 3 start triggers need for patient recruitment, site management, and data monitoring services.
  • Supply Chain Needs: Oligonucleotide platform expansion requires specialized manufacturing, cold-chain logistics, and raw material sourcing.
  • Data Infrastructure: Scaling late-stage studies increases demand for lab informatics, eCOA, and regulatory submission software.
  • Competitive Dynamics: GSK's bepirovirsen approval in Japan validates the ASO approach, raising stakes for AusperBio's differentiation.

What to Watch

Monitor AusperBio's Phase 3 enrollment progress and any partnership announcements for manufacturing or distribution. Also track GSK's bepirovirsen regulatory decisions outside Japan, which could shape market positioning. The siRNA candidate AHB-171's early clinical data will indicate platform expansion potential beyond hepatitis B.

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